ea0013oc27 | Neuroendocrinology, reproduction and cardiovascular | SFEBES2007
Chaudhri Owais
, Parkinson James
, Herlihy Amy
, Salem Victoria
, Kuo Yu-Ting
, Bell Jimmy
, So Po-Wah
, Dhillo Waljit
, Stanley Sarah
, Ghatei Mohammad
, Bloom Steve
The rise in the prevalence of obesity has imparted urgency to the study of the mechanisms of appetite regulation. Oxyntomodulin (OXM) and glucagon-like peptide-1 (GLP-1) are anorexigenic gut hormones thought to act via the same receptor. There is an increasing body of evidence, however, that they may act via distinct pathways. Magnetic resonance imaging (MRI) is increasingly being used as a tool for tracking changes in neuronal activity in vivo through time. Manganese-e...